- Uniswap Labs President Mary-Catherine Lader has stepped down after four years.
- She will advise the firm while pursuing a new venture.
Uniswap Labs is seeing a key leadership change. Mary-Catherine “MC” Lader, who served as President and Chief Operating Officer for four years, has stepped down to focus on a new venture while transitioning to an advisory role at the firm.
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A Career Spanning Wall Street and DeFi
Before joining Uniswap in 2021, Lader held a prominent position at BlackRock as Managing Director and Global Head of Aladdin Sustainability. Her move to Uniswap marked a significant shift from traditional finance to the emerging DeFi space. Lader was among the early Wall Street professionals who recognized the potential of decentralized finance during a period dominated by price volatility, hacks, and scams.
At Uniswap, Lader played a pivotal role in scaling the startup’s team and operations. Her leadership contributed to the platform’s growth, including supporting product development and strengthening its presence in the DeFi ecosystem. A spokeswoman for Uniswap expressed gratitude for her contributions, stating the company will continue building on her work while focusing on its users, partners, and broader DeFi community.
Uniswap Growth and Milestones
Founded in 2018 by Hayden Adams, Uniswap’s revolutionized decentralized trading by developing the Uniswap’s protocol, a peer-to-peer crypto exchange built on Ethereum. The firm has experienced significant growth, most recently raising $165 million in a Series B funding round in October 2022, which valued the company at approximately $1.66 billion. Earlier this year, Uniswap launched its own blockchain, Unichain, further expanding its ecosystem.
Trading activity on Uniswap remains robust, with around $83 billion in trading volume recorded in June 2025, according to data from DeFi tracker DefiLlama. These milestones underline the platform’s increasing influence within the decentralized finance market.
Regulatory Challenges Overcome
Uniswap has also navigated complex regulatory challenges. In February 2025, the US Securities and Exchange Commission (SEC) concluded an investigation into the company without taking enforcement action. The SEC had previously sent a Wells Notice, signaling potential legal action, alleging that Uniswap operated as an unregistered broker and exchange while issuing unregistered securities. The resolution was a significant relief for the DeFi platform and its community.
As Mary-Catherine Lader moves on to her next venture, the DeFi sector will closely watch her future endeavors. Meanwhile, Uniswap Labs continues to strengthen its position as a major player in decentralized finance.
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